姓名:丁莉芸

丁莉芸,女,教授,博导,湖北省杰出青年基金获得者(2021)。2022年起至今,任兰州大学物理科学与技术学院教授,2015至2022年任武汉理工大学光纤传感技术与网络国家工程研究中心研究员,长期从事光学敏感纳米复合材料的设计与制备、传感技术理论、光纤化学与生物传感器等基础研究及产业转化工作,研究领域涉及物理、材料、微电子和医学等交叉学科。担任甘肃省功能基因组与分子诊断重点实验室副主任,中国光学学会光学测试专业委员会委员。 主持国家自然科学基金项目4项、中央引导地方科技发展专项课题1项、甘肃省自然科学基金重大专项课题1项、以及省/部级科研项目十余项;作为学术骨干参与多项国家自然科学基金重点项目、杰青项目及面上项目等。发表高水平学术论文100余篇,包括Biosensors & Bioelectronics, Sensors and Actuators B-Chemical, Acs Applied Materials & Interfaces等生化分析及传感器领域Top期刊,ISI 统计SCI 论文被引用2100 多次,H因子为25;申请发明专利13项(其中一项专利已获转让)。

科研与学术工作经历:

(1) 2022.06---至 今, 兰州大学,物理科学与技术学院, 教授

(2) 2015.10---2022.05, 武汉理工大学,光纤传感技术与网络国家工程研究中心, 研究员

(3) 2019.09---2020.08, 加拿大阿尔伯塔大学, 化学与工程学院, 访问学者

(4) 2013.02---2014.02, 澳大利亚阿德莱德大学, 先进光电子技术研究中心, 访问学者

(5) 2009.10---2015.09, 武汉理工大学, 光纤传感技术与网络国家工程研究中心, 副研究员

(6) 2007.06---2009.09, 武汉理工大学, 光纤传感技术与网络国家工程研究中心, 讲师

教育经历:

(1) 2004.09---2007.06, 武汉理工大学, 光电子及信息材料, 博士

(2) 2001.09---2004.06, 武汉理工大学, 材料加工与工程, 硕士

(3) 1997.09---2001.07, 武汉理工大学, 无机非金属材料, 学士

以开发新型光学传感敏感材料为研究基础,创新性地结合光纤传感技术研制新型光纤化学与生物传感器,开发具有自主知识产权的微型化、高灵敏度的实时在体监测技术,为环境与食品、生物医学等领域提出了检测新思路。

1、光纤化学与生物传感器 2、光电功能纳米材料与器件 3、光纤传感原理计算与模拟

教学情况: 承担博、硕士课程《智能材料与结构》、《光纤化学与生物传感器》; 本科生课程《安全工程》。

指导研究生情况: 已培养博士研究生2名、硕士研究生25名; 正在指导博士研究生3名,硕士研究生10名。

发表标志性论文:

[1] Jianfeng Chen, Liyun Ding*, Jue Zhao, Xingdong Jiang, Fei Ma, Haijun Li*, Yumei Zhang. A L-glutamine binding protein modified MNM structured optical fiber biosensor based on surface plasmon resonance sensing for detection of L-glutamine metabolism in vitro embryo culture. Biosensors & Bioelectronics, 2023; 237, 115537. SCIE收录; IF/JCR分区:12.6/Q1(生化分析及传感器Top顶刊)

[2]Yumei Zhang, Liyun Ding*, Haowen Zhang, Pan Wang, Haijun Li*. A new optical fiber biosensor for acetylcholine detection based on pH sensitive fluorescent carbon quantum dots. Sensors and Actuators: B. Chemical. 2022; 369, 132268. SCIE收录; IF/JCR分区: 9.221/Q1(生化分析及传感器Top期刊)

[3]Yu Sha, Ding Liyun*, Lin Haitao, Wu Wei, Huang Jun. A novel optical fiber glucose biosensor based on carbon quantum dots-glucose oxidase/cellulose acetate complex sensitive film. Biosensors & Bioelectronics. 2019; 146, 111760. SCIE收录; IF/JCR分区: 12.618/Q1 (生化分析及传感器Top期刊)

[4] Xu Bing, Huang Jun, Xu Xiaofeng, Zhou Ai, Ding Liyun*. Ultrasensitive NO Gas Sensor Based on the Graphene Oxide-Coated Long-Period Fiber Grating. Acs Applied Materials & Interfaces. 2019; 11(43): 40868-40874. SCIE收录; IF/JCR分区: 9.229/Q1(材料科学Top期刊)

[5] Ding Liyun*, Ruan Yinlan, Li Tao, Huang Jun, Stephen C. Warren-Smith, Heike Ebendorff-Heidepriem, Tanya M. Monro. Nitric oxide optical fiber sensor based on exposed core fibers and CdTe/CdS quantum dots. Sensors and Actuators B-Chemical. 2018; 273: 9-17. SCIE收录; IF/JCR分区: 9.221/Q1(生化分析及传感器Top期刊)

[6] Ding Liyun*, Li Zhijie, Ding Qingjun, Shen Xiang, Yuan Yinquan, Huang Jun. Microstructured optical fiber based chloride ion sensing method for concrete health monitoring. Sensors and Actuators B-Chemical. 2018; 260:763-769. SCIE收录; IF/JCR分区: 9.221/Q1(生化分析及传感器Top期刊)

[7] Xu Bing, Huang Jun, Ding Liyun*, Cai Jun. Graphene oxide-functionalized long period fiber grating for ultrafast label-free glucose biosensor. Materials Science & Engineering C-Materials for Biological Applications. 2020; 107, 110329. SCIE收录; IF/JCR分区: 7.328/Q1

[8] Lin Haitao, Huang Jun, Ding Liyun*, A Recyclable Optical Fiber Sensor Based on Fluorescent Carbon Dots for the Determination of Ferric Ion Concentrations. Journal of Lightwave Technology, 2019. 37(18): p. 4815-4822. SCIE收录; IF/JCR分区: 4.142/ Q1; (Top期刊)

其他发表论文(近五年按时间倒序)

[1] Liyun Ding*, Shiyuan Wang, Qin Li, Yumei Zhang, Jue Zhao, Xingdong Jiang, Fei Ma*. Dual-mode cholesterol sensor based on gold nanorods and carbon quantum dots. Materials Chemistry and Physics, 2023; 309, 128336. SCIE收录; IF/JCR分区:4.6/Q2

[2] Hui Wu, Liyun Ding*, Gang Long, Xingdong Jiang, Fei Ma. Preparation of a high stability optical fiber oxygen sensor based on the bilayer sensitive membrane. Optical Fiber Technology. 2023; 77, 103258. SCIE收录; IF/JCR分区:4.3/Q2

[3] Wu Fang, Liyun Ding*, Yumei Zhang, Haijun Li. Prism SPR Glucose Sensor Based on Gold Nanoparticle/Gold Film Coupling Enhanced SPR. IEEE Sensors Journal. 2023, 23(12), 12477-12484. SCIE收录; IF/JCR分区:4.3/Q2

[4] Bing Xu, Xiaoying Xiang, Liyun Ding*, Zhihui Luo, Jue Zhao, Jun Huang, Haijun Li*, and Xingdong Jiang. A Novel Large-Diameter Optical Fiber Glucose Biosensor Based on Glucose Oxidase–Graphene Oxide–Gold Nanoparticles. IEEE Sensors Journal, 2023, 23(7), 6832-6839. SCIE收录; IF/JCR分区:4.3/Q2

[5] Liyun Ding*, Gang Long, Haowen Zhang, Yumei Zhang, Xingdong Jiang*, Juanjuan Zuo*. Simulation of the spectral properties and photothermal effects of homogeneously dispersed solution of gold nanorods. Materials Today Communications, 2023; 37, 106876. SCIE收录; IF/JCR分区:3.8/Q2

[6] Botao Zhang, Liyun Ding*, Yumei Zhang, Shiyuan Wang, Xingdong Jiang, Fei Ma and Jue Zhao. An oPD-CDs doped zirconium-based metal-organic frame composite fluorescence probe for the efficient and selective detection of nitric oxide. New Journal of Chemistry. 2023; 47(26), 12200-12207. SCIE收录; IF/JCR分区:3.3/Q2

[7] Tian Wu, Liyun Ding*, Yumei Zhang, Wu Fang. A simple cortisol biosensor based on AuNPs-DNA aptamer conjugate. IEEE Sensors Journal. 2022; 22(13), 12485-12492. SCIE收录; IF/JCR分区: 4.325/Q2.

[8] Qin Li, Liyun Ding*, Yumei Zhang, Tian Wu, A Cholesterol Optical Fiber Sensor Based on CQDs-COD/CA Composite, IEEE Sensors Journal, 2022. 22(7): 6247-6255. SCIE收录; IF/JCR分区: 4.325/Q2

[9] Haowen Zhang, Liyun Ding*, Yumei Zhang, Tian Wu, Qin Li, Adsorption of graphene oxide with cellulose acetate: insights from DFT, Molecular Physics, 2022. e2044083. SCIE收录; IF/JCR分区: 1.962/ Q4

[10] Wu Wei, Huang Jun, Ding Liyun*, Lin Haitao, Yu Sha, Yuan Fang, Liang Bing, A real-time and highly sensitive fiber optic biosensor based on the carbon quantum dots for nitric oxide detection. J. Photochemistry and Photobiology a-Chemistry, 2021. 405(15).112963. SCIE收录; IF /JCR分区: 4.291/Q2

[11] Ding Liyun*, Gong Panfeng, Xu Bing, Ding Qingjun, An Optical Fiber Sensor Based on Fluorescence Lifetime for the Determination of Sulfate Ions. Sensors, 2021. 21(954). SCIE收录; IF /JCR分区: 3.576/ Q2

[12] Bing Xu, Jun Huang, Liyun Ding*, Hao Zhang, Haowen Zhang, A Sensitive ammonia sensor using long period fiber grafting coated with graphene Oxide/cellulose acetate. Ieee Sensors Journal, 2021. 21: p.16691-16700. SCIE收录; IF /JCR分区: 3.301/ Q2

[13] Xiong Huizhi, Ding Liyun*, Xu Bing, Liang Bing, Yuan Fang, A Versatile Optical Fiber Sensor Comprising an Excitation-Independent Carbon Quantum Dots/Cellulose Acetate Composite Film for Adrenaline Detection. Ieee Sensors Journal, 2021. 21(9): p. 10392-10399. SCIE收录; IF /JCR分区: 3.301/ Q2

[14] Cai Jun, Ding Liyun*, Gong Panfeng, Huang Jun, A colorimetric detection of microRNA-148a in gastric cancer by gold nanoparticle-RNA conjugates. Nanotechnology, 2020. 31(9). SCIE收录; IF /JCR分区: 3.847/ Q2

[15] He Jianyu, Ding Liyun*, Cai Jun, Zhu Wenjie, Dai Jixiang, A novel high temperature resistant Mo-Cu functional gradient coating for optic fiber Bragg grating. Results in Physics, 2019. 14. SCIE收录; IF/JCR分区: 4.476/ Q2

[16] Xiao Wu, Ding Liyun*, He Jianyu, Huang Jun, Preparation of lucigenin-doped silica nanoparticles and their application in fiber optic chloride ion sensor. Optical Materials, 2019. 98, 109467. SCIE收录; IF/JCR分区: 3.080/ Q2

[17] Li Zhijie, Stoffel Mathieu, Ding Liyun*, Rouxel Didier*, Ding Qingjun, Synthesis of hydrophilic P(VDF-TrFE) chloride sensitive polymer films for fluorescence sensing. Journal of Polymer Research, 2019. 26(12). SCIE收录; IF/JCR分区: 3.097/ Q3

[18] Lin Haitao, Huang Jun, Ding Liyun*, Preparation of Carbon Dots with High-Fluorescence Quantum Yield and Their Application in Dopamine Fluorescence Probe and Cellular Imaging. Journal of Nanomaterials, 2019. 2019, p. 1-9. SCIE收录; IF/JCR分区: 2.986/ Q3

[19] Liu Dengwu, Xia Zhilin*, Shi Kailiang, Jiang Xiaosu, Yu Zhongquan, Zhang Zhenfei, Fang Zhen, Ding Liyun*, Meng Zhenghua, A thermally stable cooler for efficient passive radiative cooling throughout the day. Optical Materials, 2019. 92: p. 330-334. SCIE收录; IF/JCR分区: 3.080/ Q2

[20] Lin Haitao, Li Mengshi, Ding Liyun*, Huang Jun, A Fiber Optic Biosensor Based on Hydrogel-Immobilized Enzyme Complex for Continuous Determination of Cholesterol and Glucose. Applied Biochemistry and Biotechnology, 2019. 187(4): p. 1569-1580. SCIE收录; IF/JCR分区: 2.926/ Q3

[21] Ding Liyun*, Xu Bing, Li Tao, Huang Jun, Bai Wei, A "Turn-On" Fluorescence Copper Biosensor Based on DNA Cleavage-Dependent Graphene Oxide-dsDNA-CdTe Quantum Dots Complex. Sensors, 2018. 18(8). SCIE收录; IF /JCR分区: 3.576/ Q2

[22] Lin Haitao, Ding Liyun*, Zhang Bingyu, Huang Jun*, Detection of nitrite based on fluorescent carbon dots by the hydrothermal method with folic acid. Royal Society Open Science, 2018. 5(5). SCIE收录; IF /JCR分区: 2.963/ Q2

申请专利情况:

[1] 丁莉芸; 张浩文; 徐冰; 黄俊, 基于氧化石墨烯/乙酸纤维素的长周期光纤光栅NH3气体传感器, 中国专利,专利号:ZL202110458439.9.

[2] 丁莉芸;何光辉;郭会勇;徐一旻;王月明;姜德生,一种解决余长问题的光纤光栅阵列测温光缆及工艺,中国专利,申请专利号:CN202010568464.8.

[3] 丁莉芸;吴伟;林海涛;余莎;徐冰;黄俊,一种用于NO检测的高量子产率碳量子点制备方法及其应用,中国专利,申请专利号:CN201910387458.X。

[4] 丁莉芸;徐冰;肖武;何建宇;黄俊,基于石墨烯长周期光纤光栅传感器,中国专利,专利号:ZL201810048451.0。

[5] 丁莉芸;吴伟;林海涛;余莎;徐冰;黄俊,基于简化微结构光纤的超灵敏传感器,中国专利,专利号:ZL201810450829.X。

[6] 丁莉芸;蔡俊;何建宇;徐冰;肖武;黄俊,具有梯度结构涂覆层的耐高温光纤,中国专利,专利号:ZL201810044940.9。

[7] 丁莉芸;林海涛;黄俊;王星瑞,一种具有高荧光量子产率碳量子点的制备方法及其在细胞成像中的应用,中国专利,专利号:CN201710970061.4。

[8] 丁莉芸;徐创;徐冰;黄俊,用于检测胚胎代谢产物的光纤传感器及其制作方法,中国专利,专利号:ZL201611029589.3。

[9] 丁莉芸;黄俊;袁银权;钟韵鸣;李大鹏;范超童;伊琳,量子点聚合物复合一氧化氮荧光探针及其制备方法,中国专利,专利号:ZL201210000664.9。(已转让)

[10] 丁莉芸;黄俊;戴玉堂;黄兰芬;王海;钟韵鸣,用于检测生物体内一氧化氮浓度的微型光纤生物传感器,中国专利,专利号:ZL200910273390.9。

1、国家自然科学基金委,面上项目,62475109,面向体外胚胎发育评估体系实时在线监测的多参数微结构光纤生物传感器研究,2025/01/01-2028/12/31,主持;

2、中央引导地方科技发展专项,基于新型光纤探头的急性肾损伤早期多参数尿液无创诊断体系构建与应用,2024/07/01-2026/06/30; 

3、国家自然科学基金委,面上项目,51878524,基于微结构光纤传感器实时监测的混凝土中氯离子渗透特性的研究,2019/01/01-2022/12/31,主持;

4、国家自然科学基金委,面上项目,61575150,基于开放大空气孔微结构光纤的超灵敏NO传感器研究,2016/01/01-2019/12/31,主持;

5、国家自然科学基金委,青年科学基金项目,50802069,实时在体NO光纤微型生物传感器的材料研究,2009/01/01-2011/12/31,主持;

6、湖北省自然科学基金委,杰出青年基金项目,2021CFA041,基于微结构光纤的新型生物传感器研究 ,2021/10/01-2024/09/30, 主持;

7、湖北省自然科学基金委,面上项目,2014CFB831,基于石墨烯/量子点的新型光纤葡萄糖传感器研究,2014/01/01-2015/12/31,主持;

8、中央高校基本科研专项基金4项,主持;

9、企业横向项目2项,主持.

研究生招生: 招收凝聚态物理、微电子学与固体电子学专业博士和硕士研究生,微电子专业硕士研究生。

【联系方式】

单位:兰州大学物理科学与技术学院 地址:730000甘肃省兰州市城关区天水南路222号

办公室:城关校区(西区)格致楼5002

电子邮件:dingly@lzu.edu.cn